Oncoplex Mutation Detection

Incorporating the GeneFirst MMD (Multiplex Mutation Detection) technology, Oncoplex Mutation Detection kits are higly sensitive, allowing for detection of rare mutations against a high background of normal, non-mutated genomic DNA. For research-use only

Available mutation detection kits :

• ABL Mutation Detection
  The ABL assay detects T315I activating mutation in the human BCR-ABL gene with high sensitivity. 
  
  
• BRAF Mutation Detection
  ​The BRAF assay enables detection of V600E mutation in b-raf gene against a background of wild-type genomic DNA. 
  
  
• EGFR Mutation Detection
  ​EGFR Mutation Detection kit enables in four closed-tube reactions detection of 29 different somatic EGFR mutations - both activating and resistance - against a background of wild-type genomic DNA. 
  
  
• ​JAK2 Mutation Detection
  JAK2-MMD-PCR Mutation Test Kit enables detection of V617F mutation in jak2 gene against a background of wild-type genomic DNA. 
  
  
• KRAS Mutation Detection
  ​Kras-MMD-PCR Mutation Test Kit enables in two closed-tube reactions detection of seven most common k-ras mutations in codons 12 and 13 against a background of wild-type genomic DNA. 
  
  
• NRAS Mutation Detection
  ​The NRAS Mutation Detection Test Kit detects 23 mutations in codons 12, 13, 117 and 146 of the human NRAS gene against a background of wild-type genomic DNA. 
  
  
• ​PIK3CA Mutation Detection
  The PIK3CA Mutation Detection Kit enables in one closed-tube reaction detection of four different PIK3CA mutations against background of wild-type genomic DNA. The kit allows distinguishing mutations in exon 9 (detected in FAM channel) from mutation in exon 20 (detection in HEX channel).

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