Oncoplex Mutation Detection
Incorporating the GeneFirst MMD (Multiplex Mutation Detection) technology, Oncoplex Mutation Detection kits are higly sensitive, allowing for detection of rare mutations against a high background of normal, non-mutated genomic DNA. For research-use only
Available mutation detection kits :
- ABL Mutation Detection
The ABL assay detects T315I activating mutation in the human BCR-ABL gene with high sensitivity.
- BRAF Mutation Detection
The BRAF assay enables detection of V600E mutation in b-raf gene against a background of wild-type genomic DNA.
- EGFR Mutation Detection
EGFR Mutation Detection kit enables in four closed-tube reactions detection of 29 different somatic EGFR mutations - both activating and resistance - against a background of wild-type genomic DNA.
- JAK2 Mutation Detection
JAK2-MMD-PCR Mutation Test Kit enables detection of V617F mutation in jak2 gene against a background of wild-type genomic DNA.
- KRAS Mutation Detection
Kras-MMD-PCR Mutation Test Kit enables in two closed-tube reactions detection of seven most common k-ras mutations in codons 12 and 13 against a background of wild-type genomic DNA.
- NRAS Mutation Detection
The NRAS Mutation Detection Test Kit detects 23 mutations in codons 12, 13, 117 and 146 of the human NRAS gene against a background of wild-type genomic DNA.
- PIK3CA Mutation Detection
The PIK3CA Mutation Detection Kit enables in one closed-tube reaction detection of four different PIK3CA mutations against background of wild-type genomic DNA. The kit allows distinguishing mutations in exon 9 (detected in FAM channel) from mutation in exon 20 (detection in HEX channel).